产品货号：
Z12885
中文名称：
BST2抗体
英文名称：
Anti-BST2 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-BST2 Antibody |
| 指标别名 | Bone marrow stromal antigen 2;BST 2;BST2;CD317;HM1.24 antigen;Tetherin |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | ELISA,WB |
| 基因名称 | BST2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Bst2 antibody was raised against a 18 amino acid synthetic peptide near the amino terminus of the mouse Bst2.The immunogen is located within amino acids 60 - 110 of Bst2. |
| 计算分子量 | 19kDa |
| 成分 | Bst2 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | Bst2 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Bst2 was first identified as a novel terminal B-cell-restricted antigen termed HM1.24 that is expressed on certain bone marrow cells as well as other tissues.The surface expression of Bst2 on fibroblast cell lines facilitated the stromal cell-dependent growth of DW34,a pre-B-cell line,suggesting that this protein is involved in pre-B-cell growth.Later experiments also showed it to be upregulated in several myeloma cells.More recently,Bst2 was identified an inhibitor of retroviral release from human cells whose activity is antagonized by the HIV-1 accessory protein Vpu.While Bst2 caused retention of virions on cell surfaces or endocytosis into Bst2-positive compartments,its depletion abolished the viral requirement for Vpu for virus release.This activity may represent a potential therapeutic strategy for the treatment of HIV/AIDS. |
| Uniprot ID | Q8R2Q8 |
| 基因名全称 | Bone marrow stromal cell antigen 2 |
| 蛋白名全称 | Bone marrow stromal cell antigen 2 |
| 推荐稀释比 | Bst2 antibody can be used for detection of Bst2 by Western blot at 1 ～ 2μg/mL.Antibody validated:Western Blot in human samples.All other applications and species not yet tested. |
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